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New variant may reduce vaccine efficacy

New variant may reduce vaccine efficacy

THE new COVID-19 variant identified in South Africa can evade the antibodies that attack it in treatments using blood plasma from previously recovered patients and may reduce the efficacy of the current line of vaccines, scientists have said. Researchers are racing to establish whether the vaccines currently being rolled out across the globe are effective against the so-called 501Y.V2 variant, identified by South African genomics experts late last year in Nelson Mandela Bay. "This lineage exhibits complete escape from three classes of therapeutically relevant monoclonal antibodies," the team of scientists from three South African universities working with the National Institute…
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Blood plasma trial finds no benefit for severely ill patients

Blood plasma trial finds no benefit for severely ill patients

KATE KELLAND AN international trial testing convalescent blood plasma in cases of moderate and severe COVID-19 has halted enrolment of severely ill patients requiring intensive care after finding the plasma was of no benefit, trial investigators have said The decision by the REMAP-CAP trial leaders came after an initial analysis of more than 900 severely ill trial participants in intensive care showed that treatment with the product - an antibody-rich plasma taken from people who have recovered from the pandemic disease - did not improve outcomes. "There was no evidence of harm associated with the administration of convalescent plasma" (and)…
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